{"id":5145,"date":"2022-06-30T07:11:54","date_gmt":"2022-06-30T07:11:54","guid":{"rendered":"https:\/\/mdr.foobrdigital.com\/?p=5145"},"modified":"2022-06-30T07:11:54","modified_gmt":"2022-06-30T07:11:54","slug":"crossed-aldol-condensation","status":"publish","type":"post","link":"https:\/\/mudassirbackup.infinitycodestudio.com\/index.php\/2022\/06\/30\/crossed-aldol-condensation\/","title":{"rendered":"Crossed Aldol Condensation"},"content":{"rendered":"\n<p>The condensation reaction between two different molecules of an\u00a0aldehyde or ketone\u00a0in a protic solvent such as water or alcohol constitutes the crossed aldol reaction. When condensation is between two different carbonyl compounds, it is called crossed aldol condensation. When both aldehydes have alpha hydrogens, both can form carbanions and can also act as carbanion acceptors. Hence a mixture of four products is formed which has little synthetic value.<\/p>\n\n\n\n<p>If one of the aldehydes has no alpha hydrogen then it can act only as a carbanion acceptor. In such a case, only two products are formed. A common substrate for the crossed aldol reaction is an\u00a0aromatic aldehyde, which has no alpha position. Furthermore, dehydration of the initial condensation product is rapid which leads to the formation of the \u03b1, \u03b2 \u2013 unsaturated ketone and prevents the retro-aldol reaction from taking place.<\/p>\n\n\n\n<h3 class=\"wp-block-heading\"><img loading=\"lazy\" decoding=\"async\" src=\"https:\/\/cdn1.byjus.com\/wp-content\/uploads\/2018\/07\/Crossed-Aldol-Condensation2-700x262.png\" alt=\"Crossed Aldol Condensation\" width=\"700\" height=\"262\" srcset=\"https:\/\/cdn1.byjus.com\/wp-content\/uploads\/2018\/07\/Crossed-Aldol-Condensation2.png 700w, https:\/\/cdn1.byjus.com\/wp-content\/uploads\/2018\/07\/Crossed-Aldol-Condensation2-250x94.png 250w, https:\/\/cdn1.byjus.com\/wp-content\/uploads\/2018\/07\/Crossed-Aldol-Condensation2-120x45.png 120w\"><\/h3>\n","protected":false},"excerpt":{"rendered":"<p>The condensation reaction between two different molecules of an\u00a0aldehyde or ketone\u00a0in a protic solvent such as water or alcohol constitutes the crossed aldol reaction. When condensation is between two different carbonyl compounds, it is called crossed aldol condensation. When both aldehydes have alpha hydrogens, both can form carbanions and can also act as carbanion acceptors. [&hellip;]<\/p>\n","protected":false},"author":1,"featured_media":0,"comment_status":"open","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[603],"tags":[],"_links":{"self":[{"href":"https:\/\/mudassirbackup.infinitycodestudio.com\/index.php\/wp-json\/wp\/v2\/posts\/5145"}],"collection":[{"href":"https:\/\/mudassirbackup.infinitycodestudio.com\/index.php\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/mudassirbackup.infinitycodestudio.com\/index.php\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/mudassirbackup.infinitycodestudio.com\/index.php\/wp-json\/wp\/v2\/users\/1"}],"replies":[{"embeddable":true,"href":"https:\/\/mudassirbackup.infinitycodestudio.com\/index.php\/wp-json\/wp\/v2\/comments?post=5145"}],"version-history":[{"count":0,"href":"https:\/\/mudassirbackup.infinitycodestudio.com\/index.php\/wp-json\/wp\/v2\/posts\/5145\/revisions"}],"wp:attachment":[{"href":"https:\/\/mudassirbackup.infinitycodestudio.com\/index.php\/wp-json\/wp\/v2\/media?parent=5145"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/mudassirbackup.infinitycodestudio.com\/index.php\/wp-json\/wp\/v2\/categories?post=5145"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/mudassirbackup.infinitycodestudio.com\/index.php\/wp-json\/wp\/v2\/tags?post=5145"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}