{"id":5174,"date":"2022-06-30T07:36:20","date_gmt":"2022-06-30T07:36:20","guid":{"rendered":"https:\/\/mdr.foobrdigital.com\/?p=5174"},"modified":"2022-06-30T07:36:20","modified_gmt":"2022-06-30T07:36:20","slug":"mechanism","status":"publish","type":"post","link":"https:\/\/mudassirbackup.infinitycodestudio.com\/index.php\/2022\/06\/30\/mechanism\/","title":{"rendered":"Mechanism"},"content":{"rendered":"\n<p>The Friedel-Crafts alkylation reaction proceeds via a three-step mechanism.<\/p>\n\n\n\n<h4 class=\"wp-block-heading\">Step 1<\/h4>\n\n\n\n<p>The\u00a0Lewis acid\u00a0catalyst (AlCl<sub>3<\/sub>) undergoes reaction with the alkyl halide, resulting in the formation of an electrophilic carbocation.<\/p>\n\n\n\n<h4 class=\"wp-block-heading\">Step 2<\/h4>\n\n\n\n<p>The carbocation proceeds to attack the aromatic ring, forming a cyclohexadienyl cation as an intermediate. The aromaticity of the arene is temporarily lost due to the breakage of the carbon-carbon double bond.<\/p>\n\n\n\n<h4 class=\"wp-block-heading\">Step 3<\/h4>\n\n\n\n<p>The deprotonation of the intermediate leads to the reformation of the carbon-carbon double bond, restoring aromaticity to the compound. This proton goes on to form hydrochloric acid, regenerating the AlCl<sub>3<\/sub>&nbsp;catalyst.<\/p>\n\n\n\n<figure class=\"wp-block-image aligncenter size-full\"><img decoding=\"async\" src=\"https:\/\/mdr.foobrdigital.com\/wp-content\/uploads\/2022\/06\/sir.png\" alt=\"\" class=\"wp-image-5175\" title=\"Friedel-Crafts Alkylation Reaction Mechanism\"\/><\/figure>\n\n\n\n<p>An illustration describing the mechanism of the Friedel-Crafts alkylation reaction is provided above.<\/p>\n","protected":false},"excerpt":{"rendered":"<p>The Friedel-Crafts alkylation reaction proceeds via a three-step mechanism. Step 1 The\u00a0Lewis acid\u00a0catalyst (AlCl3) undergoes reaction with the alkyl halide, resulting in the formation of an electrophilic carbocation. Step 2 The carbocation proceeds to attack the aromatic ring, forming a cyclohexadienyl cation as an intermediate. The aromaticity of the arene is temporarily lost due to [&hellip;]<\/p>\n","protected":false},"author":1,"featured_media":0,"comment_status":"open","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[689],"tags":[],"_links":{"self":[{"href":"https:\/\/mudassirbackup.infinitycodestudio.com\/index.php\/wp-json\/wp\/v2\/posts\/5174"}],"collection":[{"href":"https:\/\/mudassirbackup.infinitycodestudio.com\/index.php\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/mudassirbackup.infinitycodestudio.com\/index.php\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/mudassirbackup.infinitycodestudio.com\/index.php\/wp-json\/wp\/v2\/users\/1"}],"replies":[{"embeddable":true,"href":"https:\/\/mudassirbackup.infinitycodestudio.com\/index.php\/wp-json\/wp\/v2\/comments?post=5174"}],"version-history":[{"count":0,"href":"https:\/\/mudassirbackup.infinitycodestudio.com\/index.php\/wp-json\/wp\/v2\/posts\/5174\/revisions"}],"wp:attachment":[{"href":"https:\/\/mudassirbackup.infinitycodestudio.com\/index.php\/wp-json\/wp\/v2\/media?parent=5174"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/mudassirbackup.infinitycodestudio.com\/index.php\/wp-json\/wp\/v2\/categories?post=5174"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/mudassirbackup.infinitycodestudio.com\/index.php\/wp-json\/wp\/v2\/tags?post=5174"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}